Description of St. John's Wort Extract:
St. John's wort extract has been used for centuries to calm the nerves and treat depression. It also has been used to dress wounds, heal deep cuts, smooth burns and ease the pain of neuralgias. Taken internally, it has been used for ulcers and gastritis. An infusion of the herb has also been used as an expectorant for bronchitis, a diuretic for the kidneys and an easing agent for menstrual cramps.
Sources of St. John's Wort Extract
St.John's wort is widely known as an herbal treatment for depression.St.John's wort also alleviated age-related long-term memory impairment .
Hypericum perforatum is a perennial herb from Hypericum. According to the latest results of an experimental study, confirmed by the hypericin in Hypericum perforatum extracts, to treat patients with moderate depression, and very few adverse side effects .
Ingredients of St. John's Wort Extract
Hypericin 0.3%
Specification of St. John's Wort Extract
| Item | Specification |
| Active Ingredient | |
| hypericin | 0.3% |
| Physical Control | |
| Identification | Positive |
| Appearance | brown yellow fine powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Sieve Analysis | 100% pass 80 mesh |
| Loss on Drying | 5% Max |
| Ash | 3% Max |
| Chemical Control | |
| Arsenic (As) | NMT 2ppm |
| Lead (Pb) | NMT 2ppm |
| Heavy Metals | 20ppm Max |
| Microbiological Control | |
| Total Plate Count | 5000cfu/g Max |
| Yeast & Mold | 100cfu/g Max |
| E.Coli | Negative |
| Salmonella | Negative |
Study of St. John's Wort Extract
1.Applied in health product field, to be added into the health food can enhance immunity
2.Anti-depressive and sedative properties;
3.Effective remedy for the nervous system, relaxing tension, and anxiety and lifting the spirits;
4.Enhancing the effect of neurotransmitters in the brain;
5.it has significant support in the treatment of mild to modere depression ,can also help to control appetite and promotes weight loss
6.To prevent against bacterial infections
7.Applied in pharmaceutical field, it can serve as the security nerve nutrition. In Europe, it is mainly used as antidepressants.
Reference of St. John's Wort Extract
1 Linde, K; Berner, MM; Kriston, L (2008). "St John's wort for major depression". In Linde, Klaus. Cochrane Database of Systematic Reviews (4): CD000448
2 Kumar, V; Mdzinarishvili, A; Kiewert, C; Abbruscato, T; Bickel, U; van der Schyf, CJ; Klein, J (September 2006). "NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort" (PDF). Journal of Pharmacological Sciences 102 (1): 47–54.
3 Saito, YA; Rey, E; Almazar-Elder, AE; Harmsen, WS; Zinsmeister, AR; Locke, GR; Talley, NJ (January 2010). "A randomized, double-blind, placebo-controlled trial of St John's wort for treating irritable bowel syndrome". Am. J. Gastroenterol. 105 (1): 170–7.
4 Ernst, E; Rand, JI; Barnes, J; Stevinson, C (1998). "Adverse effects profile of the herbal antidepressant St. John's wort (Hypericum perforatum L.)". European Journal of Clinical Pharmacology 54 (8): 589–94.
5 Hunt, EJ; Lester, CE; Lester, EA; Tackett, RL (June 2001). "Effect of St. John's wort on free radical production". Life Sci. 69 (2): 181–90.
Wenk, M; Todesco, L; Krähenbühl, S (April 2004). "Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females" (PDF). British Journal of Clinical Pharmacology 57 (4): 495–499.
6 Woelk, H (September 2000). "Comparison of St John's wort and imipramine for treating depression: randomised controlled trial". BMJ 321 (7260): 536–9.
Schrader, E (March 2000). "Equivalence of St John's wort extract (Ze 117) and fluoxetine: a randomized, controlled study in mild-moderate depression". Int Clin Psychopharmacol 15 (2): 61–8.
7 Obach, RS (July 2000). "Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression" (PDF). Journal of Pharmacology and Experimental Therapeutics 294 (1): 88–95..
8 Kubin, A; Wierrani, F; Burner, U; Alth, G; Grünberger, W (2005). "Hypericin - The Facts About a Controversial Agent" (PDF). Current Pharmaceutical Design 11 (2): 233–253.