Description of Kudzu Extract
Latin Name: Pueraria lobata
Active Ingredient: puerarin,Isoflavones
Specification: Puerarin> 10% -98%(HPLC)
Isoflavones>40%(UV)
Isoflavones> 40%-90% (HPLC)
Test Method: HPLC&UV
CAS NO.: 3681-99-0
Botanical used part: Root
Appearance:Yellow brown Fine Powder(Pueraria Isoflavones), White Crystal Powder (Puerarin)
Molecular formula :C21H20O9
Molecular weight:416.38
Sources of Kudzu Extract
Puerara has been known for centuries in traditional Chinese medicine as ge-gen.
The first written mention of the plant as a medicine is in the ancient herbal text of Shen Nong
(about A.D.100). In traditional Chinese medicine, pueraria is used in prescriptions for the treatment of thirst, headache, and stiff neck with pain due to high blood pressure. Puerarin is also recommended for allergies, migraine headaches, inadequate measles eruptions in children, and diarrhea.Puerarin is also used in modern Chinese medicine as a treatment for angina pectoris.
Ingredients of Kudzu Extract
Active Ingredients: Puerarin, Isoflavones
CAS NO: 3681-99-0 (Puerarin)
Molecular Formula: C21H20O9
Molecular Weight: 416.38
Specification of Kudzu Extract
| ANALYSIS | SPECIFICATION |
| Appearance | Yellow brown fine powder |
| Odor | Characteristic |
| Assay(HPLC) | 40% Isoflavones / 98%Puerarin |
| Sieve analysis | 100% pass 80 mesh |
|
Loss on Drying Residue on Ignition |
≤5.0% ≤3.0% |
| Heavy Metal | <10ppm |
| As | <2ppm |
| Pb | <2ppm |
| Residual Ethanol | <0.2% |
| Residual Pesticide | <1ppm |
| Microbiology | |
| Total Plate Count | <1000 cfu/g |
| Yeast & Mold | <100 cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
Study of Kudzu Extract
Kudzu Powder Extract has been shown to be very effective in the treatment of many ailments including alcohol abuse, menopausal syndrome, phlebothrombosis, arterial obstructive disease and retina disease acute deafness, cardiac infarction, coronary heart disease, hypertension and hyperlipidemia.
(1) Dilating blood vessels, increasing coronary blood flow, antithrombotic effect, inhibiting platelet aggregation, reducing blood viscosity and promoting blood micro-cycle.
(2) Reducing myocardial oxygen consumption, strengthening myocardial contraction force and protecting myocardial cell.
(3) Enhancing immunity and inhibiting cancer cell.
(4) Treating sudden deafness of each group.
(5) Reducing the risk of cardiovascular diseases.
Reference of Kudzu Extract
1. Li J, Wang G, Liu J et al. (December 2010). "Puerarin attenuates amyloid-beta-induced cognitive impairment through suppression of apoptosis in rat hippocampus in vivo". Eur. J. Pharmacol. 649 (1–3): 195–201.
2. Sandra Lynn Burney (2010). "Determination of antioxidant and total phenolic content of Pueraria lobata and evaluation of novel food products containing kudzu"
3. Shin-ichi Kayano,Yoko Matsumura,Yoko Kitagawa, Isoflavone C-glycosides isolated from the root of kudzu (Pueraria lobata) and their estrogenic activities, Food Chemistry,134 (1), 2012: 282–287
4. Rong Li,Tao Liang,Qiaoling He,Puerarin, isolated from Kudzu root (Willd.), attenuates hepatocellular cytotoxicity and regulates the GSK-3β/NF-κB pathway for exerting the hepatoprotection against chronic alcohol-induced liver injury in rats, International Immunopharmacology,17(1),2013: 71–78
5. Przemysław Mikołajczak,Michał Szulc,Irena Okulicz-Kozaryn, Effect of kudzu (Pueraria lobata) on ghrelin blood level in alcohol Warsaw High Preferring and Warsaw Low Preferring rats, Pharmacological Reports,Volume 62, Supplement 1, September 2010, Pages 54–55
6. Nagwani Santosh,Kumar Mohan,Singh Royana,Hepatotoxicity of tubers of Indian Kudzu (Pueraria tuberosa) in rats, Food and Chemical Toxicology,48(4),2010: 1066–1071
7. Jeevan K.,Prasain,Ning Peng, The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese mice,Phytomedicine,20(1),2012: 17–23.