Product Name: Hawthorn Extract
Latin Name: Crataegus pinnatifida Bge. var.major N. E. Br.
Used Part: Fruit/leaf
2%, 8%,10% Vitexin
5%,10%,20%,30%,50% Flavones
Sources of Hawthorn Extract
Hawthorn is claimed to maintain healthy collagen matrices of arterial walls so that the vessels remain elastic.It is used to normalize heart rhythm, reduce the likelihood and severity of angina attacks, and prevent cardiac complications in elderly patients with influenza and pneumonia.Hawthorn (Crataegus species ) is a small tree or shrub and a member of the rose family. Hawthorne berriesas well as the leaves and flowershave been used in traditional medical systems since ancient times. Hawthorne (Crataegus Oxyacantha) is known as a botanical heart tonic and is recommended for angina, irregular heartbeat, high blood pressure, congestive heart failure, hypertension, coronary heart disease, high cholesterol, nervous disorders, insomnia and Raynaud's Syndrome.
Ingredients of Hawthorn Extract
Flavones/ Vitexin
Specification of Hawthorn Extract
| Assay HPLC | Vitexin 2%, 10% |
| Organoleptic | |
| Appearance | Brown to light brwon powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Physical Characteristics | |
| Particle Size | 100%Through 80 mesh |
| Loss on Drying | ≤ 5.0% |
| Ash content | ≤ 5.0% |
| Heavy Metals | |
| Total Heavy Metals | ≤10ppm |
| Pb | ≤3.0ppm |
| As | ≤1.0ppm |
| Hg | ≤0.1ppm |
| Microbiological Tests | |
| Total Plate Count | ≤5000cfu/g |
| Total Yeast & Mold | ≤500cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
Study of Hawthorn Extract
1.Improving the tolerability of mycardium to hypoxia and act against cardiac infarct like propanolol.
2.Dilating coronary artery and improving the vitality of myocardium.
3.Decreasing blood lipids,blood pressure and the cerebral vascular resistance
4.Act against arrhythmia,expecially atrial or ventricular premature beats,but have no effect on effect on atrial fibrillation.
5.Significantly suppress the platelet aggregation induced by collagen
Reference of Hawthorn Extract
1 Ching-Yee Kwok,Chang Li,Huan-Le Cheng, Cholesterol lowering and vascular protective effects of ethanolic extract of dried fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in diet-induced hypercholesterolaemic rat model,Functional food,5(3),2013:1326-1335
2 Tongxun Liu,Yanni Cao, Mouming Zhao, Extraction optimization, purification and antioxidant activity of procyanidins from hawthorn (C. pinnatifida Bge. var. major) fruits, Food Chemistry,119(4),2010: 1656–1662
3 Chinnasamy Elango, Kasevan Sawaminathan Jayachandaran, Hawthorn extract reduces infarct volume and improves neurological score by reducing oxidative stress in rat brain following middle cerebral artery occlusion, International Journal of Developmental Neuroscience ,27(8), 2009: 799–803
4 W.Vierling,Investigation of the pharmaceutical and pharmacological equivalence of different Hawthorn extracts, Phytomedicine,10(1) , 2003: 8–16
5 Max H Pittler, MD,Katja Schmidt, MSc,Edzard Ernst, Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials, The American Journal of Medicine,114(8),2003: 665–674
6 Ernesto Dalli,Juana Vallés,Juan Cosín-Sales,Effects of hawthorn (Crataegus laevigata) on platelet aggregation in healthy volunteers, Thrombosis Research,128(4),2011: 398–400
7 M.H. Pittler, S. Schmidt, E. Ernst,Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials,ACC Current Journal Review,12(5),2003: 47–48
8 L.D. Li,Y.O. Li,Studies on hawthorn and its active principle, Journal of Molecular and Cellular Cardiology,19(11),1987: S24