95% Proanthocyanidin       UV

Sources of Grape Seed Extract

Grape seed extracts are industrial derivatives from whole grape seeds that have a great concentration of vitamin E, flavonoids, linoleic acid and phenolic procyanidins (also known as OPC or oligomeric procyanidins). The typical commercial opportunity of extracting grape seed constituents has been for chemicals known as polyphenols having antioxidant activity in vitro.

Ingredients of Grape Seeds Extract

95%Proanthocyanidian        UV

Specification of Grape Seed Extract

Specification of  grape seed extract
Botanical Source:	Vitis vinifera L.
Part used:	seed
Specification:	95%Proanthocyanidian      UV
Item	SPECIFICATION
Appearance	Red brown powder  (Relate to Purity)
Flavor & Odor	Characteristic
Particle size	100% pass 80 mesh
Loss on Drying	≤5.0%
Bulk density	40-60g/100ml
Sulphated Ash	≤5.0%
GMO	Free
General Status	Non-irradiated
Pb	≤3mg/kg
As	≤1mg/kg
Hg	≤0.1mg/kg
Cd	≤1mg/kg
Total microbacterial count	≤1000cfu/g
Yeast & Mold	≤100cfu/g
E.Coli	Negative
Staphylococcus aureus	Negative
Salmonella	Negative
Enterobacteriaceaes	Negative

Study of Grape Seed Extract

The grape seed extract has been linked to a wide range of possible therapeutic properties including healing wounds and treating conditions such as high cholesterol, atherosclerosis, macular degeneration, poor circulation, nerve damage, as well as preventing cancer.it increasesnatural antioxidant and anti-inflammatory concentrations and may will have a favorable effect on cardiovascular risk factors.

Reference of Grape Seed Extract

1、 Gao, N.; Budhraja, A.; Cheng, S.; Yao, H.; Zhang, Z.; Shi, X. (2009). "Induction of Apoptosis in Human Leukemia Cells by Grape Seed Extract Occurs via Activation of c-Jun NH2-Terminal Kinase". Clinical Cancer Research 15 (1): 140–9. doi:10.1158/1078-0432.CCR-08-1447. PMC 2760842.

2、 Khanna, Savita; Venojarvi, Mika; Roy, Sashwati; Sharma, Nidhi; Trikha, Prashant; Bagchi, Debasis; Bagchi, Manashi; Sen, Chandan K (2002). "Dermal wound healing properties of redox-active grape seed proanthocyanidins". Free Radical Biology and Medicine 33 (8): 1089–96..

3、 Yahara, N; Tofani, I; Maki, K; Kojima, K; Kojima, Y; Kimura, M (2005). "Mechanical assessment of effects of grape seed proanthocyanidins extract on tibial bone diaphysis in rats". Journal of musculoskeletal & neuronal interactions 5 (2): 162–9.

4、 Katiyar, Santosh K. (2008). "Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system". Molecular Nutrition & Food Research. 52 Suppl 1: S71–6.

5、 Su, X; d'Souza, DH (2011). "Grape seed extract for control of human enteric viruses". Applied and environmental microbiology 77 (12): 3982–7.

6、 Mellen, Philip B.; Daniel, Kurt R.; Brosnihan, K. Bridget; Hansen, Kim J.; Herrington, David M. (2010). "Effect of Muscadine Grape Seed Supplementation on Vascular Function in Subjects with or at Risk for Cardiovascular Disease: A Randomized Crossover Trial". Journal of the American College of Nutrition 29 (5): 469–75.

7、 Feringa, Harm H.H.; Laskey, Dayne A.; Dickson, Justine E.; Coleman, Craig I. (2011). "The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials". Journal of the American Dietetic Association 111 (8): 1173–81.

8、 Shanmuganayagam, Dhanansayan; Beahm, Mark R.; Osman, Hashim E.; Krueger, Christian G.; Reed, Jess D.; Folts, John D. (2002). "Grape Seed and Grape Skin Extracts Elicit a Greater Antiplatelet Effect When Used in Combination than When Used Individually in Dogs and Humans". The Journal of Nutrition 132 (12): 3592–8.