Hops are the female flower clusters (commonly called seed cones or strobiles), of a hop species, Humulus lupulus. They are used primarily as a flavoring and stability agent in beer, to which they impart a bitter, tangy flavor, though hops are also used for various purposes in other beverages and herbal medicine.
Xanthohumol is a prenylated flavonoid found naturally in the flowering hop plant (Humulus lupulus) which is commonly used to make the alcoholic beverage known as beer. Xanthohumol is one of the major constituents of Humulus lupulus. Xanthohumol has been reported to have sedative property, Antiinvasive effect, estrogenic activity, cancer-related bioactivities, antioxidant activity, stomachic effect, antibacterial and antifungal effects in recent studies. However, the pharmacological functions of xanthohumol on platelets were not yet understood, we are interested in investigating the inhibitory effects of xanthohumol on cellular signal transduction during the process of platelet activation.
Xanthohumol is the principal prenylated flavonoid of the female inflorescences of the hop plant (`hops'), an ingredient of beer. Human exposure to xanthohumol and related prenylflavonoids, such as 8-prenylnaringenin and isoxanthohumol, is primarily through beer consumption. Xanthohumol has been characterized a `broad-spectrum' cancer chemopreventive agent in in vitro studies, while 8-prenylnaringenin enjoys fame as the most potent phytoestrogen known to date. These biological activities suggest that prenylflavonoids from hops have potential for application in cancer prevention programs and in prevention or treatment of (post-)menopausal `hot flashes' and osteoporosis. Xanthohumol and 8-prenylnaringenin are metabolized into many flavonoid derivatives with modified 3,3-dimethyl allyl (prenyl) moieties. Xanthohumol is formed in lupulin glands by a specialized branch of flavonoid biosynthesis that involves prenylation and O-methylation of the polyketide intermediate chalconaringenin. Although a lupulin gland-specific chalcone synthase is known, the aromatic prenyltransferase and O-methyltransferase participating in xanthohumol have not been identified. The prenylflavonoid pathway is a possible target for breeding or biotechnological modification of hops with the aim of increasing xanthohumol levels for beer brewing and 8-prenylnaringenin levels for pharmaceutical production.
Benefits of Hops Extract Xanthohumol
1)With a strong estrogen-like effect
2)With the function of composure, owning composed hypnotic effects to the central nervous system
3)With the function of antibacterial, it can inhibit the growth of various bacteria. Such as bacillus anthracis, bacillus, corynebacterium diphtheriae, diplococcus pneumoniae and staphylococcus aureus
Application of Hops Extract Xanthohumol
(1) the hormonal effect of hops were noticed when female gatherers of the plants got their menstrual cycles early
(2) hops can also help to stimulate appetite ,dispel flatulence, and relieve intestinal cramps, this hervcan be usefully combined with valerian for coughs and nervous spasmodic conditions (3) hops also has diuretic properties and can be taken for various problems with water retention and excess uric acid.
Being a professional supplier of plant extract in China,Finesky can also provide pure natural high quality hops extract-xanthohumol. We can also supply other plant extract,including artichoke extract,green tea extract,milk thistle extract,epimedium extract,St. John's wort extract,grape seed extract,soybean extract,yohimbe bark extract,common cnidium extract,matrine extract,olive leaf extract,goji extract,goji dried fruit,green coffee bean extract,coenzyme Q10,pomegranate extract,kudzu extract,tribulus terrestris extract,hawthorn extract,angelica extract,dandelion extract,garlic extract,ginseng extract,echinacea purpurea extract,white willow extract,red clover extract,polygonum cuspidatum extract,pine bark extract,raspberry extract,etc.
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