Coenzyme Q10 may have a place in the treatment of some neurological diseases. A placebo-controlled clinical trial of coenzyme Q10 suggested that it can slow the rate of deterioration in patients with early-stage Parkinson disease. The consumption of up to 800 mg/day of coenzyme Q10 was well-tolerated. The trial was funded by NIH and appeared in the Archives of Neurology in 2002.
 

Coenzyme Q10 for diabetes

Coenzyme Q10 has been considered for improving glycemic control through various mechanisms, including a decrease in oxidative stress. Two earlier randomized controlled trails35,36 using 100 to 200 mg of coenzyme Q10 in patients with type 1 or 2 diabetes found no difference in glycemic control and insulin requirement. A more recent randomized controlled trial (n = 74)37 using 200 mg per day for 12 weeks found modest improvements in A1C levels (?0.37 ± 0.17 percent,P = .32).
 

Side effects and safety of Coenzyme Q10

No absolute contraindications are known for coenzyme Q10, although reliable information about its use in pregnant or breastfeeding mothers or in young children is not available. Adverse effects with coenzyme Q10 are rare. On average, mild gastrointestinal discomfort is reported in less than 1 percent of patients in clinical trials.
 

Dosage of Coenzyme Q10 supplement

The average daily dosing for adults nineteen or older is between 30mg to 150mg per day. It is important to take with food that has some fat in it, such as peanut or almond butter, for maximum absorption.
 

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