Gymnema sylvestre extract:
Gymnema sylvestre, Chinese medicine name. The roots or tender shoots of the Gymnema sylvestre (Retz.) Schult. Distribution in Zhejiang, Fujian, Taiwan, Guangdong, Hainan, Guangxi, Yunnan and other places.
English name: Gymnema Sylvestre Extract
Latin name: Gymnema sylvestre (Retz.) Schult.
Parts Used: Leaves
Active Ingredients: Gymnemic Acids
Main Specifications: Gymnemic Acids 25%, 50%, 75%
Detection method: Titration
Appearance: Light brown powder
Extraction Solvent: Ethanol
CAS NO.: 90045-47-9
Molecular formula: C43H66O14
Molecular weight: 807.00
Molecular weight: 807.00
Main Functions:
1. Hypoglycemic effect
Gymnemic acid can increase insulin sensitivity, promote insulin secretion, inhibit gluconeogenesis, and thus exert hypoglycemic effects.
2. Reduce blood fat and lose weight
Gymnema sylvestre extract can interact with some glycolytic enzymes in the body to reduce blood fat.
3. Inhibition of sweetness and anti-caries effect
Gymnema sylvestre extract has the effect of inhibiting sweet taste, and the active ingredient for inhibiting the sweet taste in the leaves of Gymnema sylvestris is saponin, which can cause loss of taste, fructose, sucrose, stevioside, xylose, there was no statistical difference in the inhibitory strength of eight sweeteners, and the average inhibition rate was 77%. In addition, gymnemic acid can significantly inhibit the activity of glucosyltransferase, block the synthesis of extracellular water-insoluble glucan of Streptococcus mutans, inhibit the formation of plaque, and cause the cariogenic bacteria to lose the cariogenic environment, thereby achieving anti-mite effect. In combination with glycyrrhizin, it can enhance the anti-caries effect and reduce the sweetness of glycyrrhizin.
4. Other pharmacological effects
Gymnema sylvestre extract also has potential anti-malarial and anti-filariasis effects; it has significant immunomodulatory effects on human neutrophils; gymnemic acid has defensive effects of radioactive substances on rat liver; Anti-breast cancer and lung cancer epithelial cell activity; inhibition of microorganisms such as bacteria and fungi.
Applications
1, Drugs,
2, Clinical medicine,
3, Health products.
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