• Gymnema Sylvestre Extract Gymnemic Acids can be used in Hypoglycemic effect and losing weight field!

  • Gymnema sylvestre extract:

    Gymnema sylvestre, Chinese medicine name. The roots or tender shoots of the Gymnema sylvestre (Retz.) Schult. Distribution in Zhejiang, Fujian, Taiwan, Guangdong, Hainan, Guangxi, Yunnan and other places. 
     
    People use Gymnema, climbing plant, as a remedy for snake bite wound for a long history, Gymnema leaves is also a kind of Chinese medicine. Because chewing the leaves can destroy the sweet taste, people give it a common name, sugar destroyer. The medicinally active parts of the plant are the leaves and the roots. Recent clinical trials conducted have shown that Gymnema sylvestre extract is useful for controlling Blood Sugar.


    English name: Gymnema Sylvestre Extract
    Latin name: Gymnema sylvestre (Retz.) Schult.
    Parts Used: Leaves
    Active Ingredients:  Gymnemic Acids
    Main Specifications:  Gymnemic Acids 25%, 50%, 75%
    Detection method: Titration
    Appearance: Light brown powder
    Extraction Solvent: Ethanol
    CAS NO.: 90045-47-9
    Molecular formula: C43H66O14
    Molecular weight: 807.00
     

     
    Main Functions:
     
    1. Hypoglycemic effect
    Gymnemic acid can increase insulin sensitivity, promote insulin secretion, inhibit gluconeogenesis, and thus exert hypoglycemic effects.
     
    2. Reduce blood fat and lose weight
    Gymnema sylvestre extract can interact with some glycolytic enzymes in the body to reduce blood fat. 
     
    3. Inhibition of sweetness and anti-caries effect
    Gymnema sylvestre extract has the effect of inhibiting sweet taste, and the active ingredient for inhibiting the sweet taste in the leaves of Gymnema sylvestris is saponin, which can cause loss of taste, fructose, sucrose, stevioside, xylose, there was no statistical difference in the inhibitory strength of eight sweeteners, and the average inhibition rate was 77%. In addition, gymnemic acid can significantly inhibit the activity of glucosyltransferase, block the synthesis of extracellular water-insoluble glucan of Streptococcus mutans, inhibit the formation of plaque, and cause the cariogenic bacteria to lose the cariogenic environment, thereby achieving anti-mite effect. In combination with glycyrrhizin, it can enhance the anti-caries effect and reduce the sweetness of glycyrrhizin.
     
    4. Other pharmacological effects
    Gymnema sylvestre extract also has potential anti-malarial and anti-filariasis effects; it has significant immunomodulatory effects on human neutrophils; gymnemic acid has defensive effects of radioactive substances on rat liver; Anti-breast cancer and lung cancer epithelial cell activity; inhibition of microorganisms such as bacteria and fungi.

    Applications
     
    1, Drugs,
    2, Clinical medicine,
    3, Health products.


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