Rhodiola rosea is a plant in the Crassulaceae family that grows in cold regions of the world. These include much of the Arctic, the mountains of Central Asia, the Rocky Mountains, and mountainous parts of Europe, such as the Alps, Pyrenees, Carpathian Mountains,Scandinavia, Iceland, Great Britain and Ireland. The perennial plant grows in areas up to 2280 meters elevation.
Rhodiola rosea contains a variety of compounds that may contribute to its effects, including the class of rosavins which include rosavin, rosarin, and rosin. Several studies have suggested that the most active components are likely to be salidroside (rhodioloside) and tyrosol, with other components being inactive when administered alone, but showing synergistic effects when a fixed combination of rhodioloside, rosavin, rosarin and rosin was used.
Rosavins 3%, salidroside 1% by HPLC
Rosavin 3% by HPLC
• Antidepressant
• Reduce fatigue and increase energy
• Mental support
Mechanism
Rhodiola rosea's effects potentially are related to optimizing serotonin and dopamine levels due to monoamine oxidase inhibition and its influence on opioid peptides such as beta-endorphins, although these specific neurochemical mechanisms have not been clearly documented with scientific studies.
Rhodiola is included among a class of plant derivatives called adaptogens which differ from chemical stimulants, such as nicotine, and do not have the same physiological effects.
In Russia and Scandinavia, Rhodiola rosea has been used for centuries to cope with the cold Siberian climate and stressful life. Such effects were provided with evidence in laboratory models of stress using the nematode C. elegans, and in rats in which Rhodiola effectively prevented stress-induced changes in appetite, physical activity, weight gain and the estrus cycle.
Safety
Rhodiola rosea Extract is safe, no side effects have been found.
Dosage
• The typical dose is 200-700mg per day (usually in 2-3 doses throughout the day).
• Consult physicians for different condition specifics.
Rhodiola rosea extract is mainly used in the form of capsules or a tablet, though tinctures are also available. The capsules and tablets often contain 100 mg of a standardized amount of 3 percent rosavins and 0.8–1 percent salidroside because the naturally occurring ratio of these compounds in Rhodiola rosea root is approximately 3:1, and of course, they contain many other suspected active biochemical compounds in the plant.
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